The Sage 6126-3 is my favorite Spey rod for late Spring to early winter. My favorite line is the Rio MidSpey 7/8 with tips. In very windy conditions, I use the W/C 678 with the upgrade.
The rod performs very well with the Skagit 450 and the Rio 15' tips. However, I feel that it performs better with the Skagit 450 and the Rio Powerflex Core Sinking leaders. The ones that seem to really work are the 12' , 126 grain, 7.0 ips and the 12' 96 grain 5.6 ips leader. In fact I'm keeping the 126 grain/7.0 ips on the line.
The Loop/Danielson 3W with 200 yards of backing is the perfect reel for this rod.
I haven't used it on the Deschutes, but it should work very well.