Can cast a regular trout line (rio gold) two handed overhead on a similar 10' 6" Meiser. Over-line a bit for overhead - a bit more if you want to try to use the trout line for spey casts. Realizing that I could overhead dries with passable delicacy (on an earlier similar light weight switch), and with OK accuracy if needed, has caused me to switch to two-handed rods for almost everything trouty.

With the right wt trout line it works OK for dries, and it is superior (to me at least) for everything else especially when you use the right line for the job.
So for example (and this is just me) on the 10' 6" 4/5 spey I might use a 6 wt rio gold for dries(overhead), a 5 or 6 wt Wulff ambush for streamers (snake rolls), and maybe even 5wt spedicator for indicator fishing. For plain nymphing where maybe the line doesn't matter too much, the longer rod works great.